2018年4月19日星期四

Difference between parents China parents and the United States parents difference

Americans do not raise children for age protection. Children are self-reliant at the age of 18. Legally, parents do not continue to support the responsibility of children over the age of 18. Children go to college after graduating from high school. Most college students work for themselves or borrow money to go to college. . American parents do not expect children to invite them to live together and take care of them when they are old; instead, they think that independence, taking care of themselves, not bringing trouble to children, and stressing children is the most dignity.

2018年4月18日星期三

How much power does the United States have for internal disturbances?

James Komi, the former head of the FBI, has violently criticized President Trump in his new book. He also accused Trump of "treating women as if they were treating a piece of meat." He continued to cast various lies and tried to convince Americans, and then came to the conclusion that "Trump is not morally suitable to serve as president of the United States." Trump was constantly attacked by his personal conduct. The number of such attacks and their scale are unprecedented among all the presidents of the United States. Many people believe that this has caused trouble for Trump to perform his duties. The United States’ federal administration system is still able to “normally operate”. This should be considered a unique scene in the United States. At this time, it should not be the period of expansion of the foreign strategy of the United States as a whole, but rather it should be its "seeking period for stability". The Trump administration has always been aggressive, but it is likely that it does not really intend to carry out a sharp collision with external forces that will burden the United States with pain because it lacks domestic unity to do so. It is probably more willing to make relatively easy victories and try to win in all directions without fighting or fighting.

2018年4月16日星期一

Ischemic heart disease, or coronary artery disease

When people think of the deadliest diseases in the world, their minds may jump to those fast-moving, incurable diseases that sometimes encounter headlines. In reality, many of these diseases are not among the top 10 causes of death worldwide. In 2015, an estimated 56.4 million people died worldwide, of which 68% was due to slow progress.


What is even more surprising is that several diseases are completely preventable. Unpreventable factors include a person's place of life, access to preventive care and quality of care. These are all risk factors. But everyone can take steps to reduce the risk.

Although it is still the main cause of death, mortality has declined in many European countries and the United States. This may be due to better public health education, access to health care and forms of prevention. However, in many developing countries, the death toll in Canada is rising. Life expectancy, socio-economic changes and lifestyle risk factors play a role in this increase.

Risk factors and prevention
CAD risk factors include:

hypertension
High cholesterol
smokes
Family history of CAD
diabetes
overweight

Talk to your doctor if you have one or more of these risk factors.
You can prevent CAD with medications and by maintaining good heart health. 

Some steps you can take to decrease your risk include:
exercising 
regularly
maintaining a healthy weight
    eating a balanced diet that’s low in sodium and high in fruits and vegetables
      avoiding smoking drinking only in moderation

    2018年4月15日星期日

    The relationship between oral cancer and HPV virus:What should we do? What should we know?

    When you hear about the increasing incidence of HPV, you might think of cervical cancer. So you might be surprised to find that this sexually transmitted virus is also the main cause of pharyngeal cancer (oropharyngeal cancer), and is transmitted between people through oral sex.

    Although oral cancer has always been associated with smoking, head and neck surgeon Brandon Prendes says current research shows that HPV is directly related to certain laryngeal cancers. In fact, these cancers are on the rise and will soon overtake new cases of cervical cancer, he said.

    According to the centers for disease control and prevention, new cases of laryngeal cancer diagnosed annually may be related to HPV. About 7% of adults have oral HPV, but only about 1% have specific types associated with throat cancer: HPV16.

    What are the risks?

    The number one risk for oral HPV infection and developing HPV associated pharyngeal cancer is multiple oral sex partners, says Dr Prendes. Having more partners increases the risk for both men and women.

    The researchers say women have fewer throat cancers associated with HPV because they may have developed an immune response against cervical cancer. Men don't have the same immunity.

    Smoking also increases risk, Dr. Prendes said. If you smoke at least a pack a day for 10 years, you are at your greatest risk.

    How do you limit your risks?

    Here are five ways to help you limit your risk of HPV-related throat cancer, according to Dr. Prendes.

    Limit number of lifetime sexual partners. The increase in risk involved with greater numbers of sexual partners is even greater for oral sexual partners. Also, use condoms or dental dams consistently for some protection.Get children and young adults vaccinated. For males and females between ages 9 and 26, a three-round HPV vaccine can ward off HPV infection.Get screened. Regular screening increases the chances you’ll catch a tumor early. Your doctor will feel your neck, examine your throat and inspect your mouth.Visit your dentist. Get regular dental checkups because dentists are often the first practitioners to notice abnormalities with the tongue and tonsils.Limit smoking and alcohol. Quit smoking and reduce alcohol consumption to cut your risk.

    What symptoms should you watch for?

    The symptoms of HPV-related throat cancer symptoms can often go largely, Dr. Prendes says, because they're difficult to recognize and categorize. If any of the symptoms lasts beyond two weeks, see your doctor or an ear, nose and throat specialist.

    Neck mass or swellingEar pain (like something is stuck in the back of your throat)Snoring (as a new issue, without sudden weight gain)

    HPV oral is slow to develop, but quick to spread.

    HPV - related working spread quickly to the lymph nodes. It 's not that the tumors spread quickly due to issues with the immune system - they spread quickly for unknown. Having clear that they show up first as large swollen lymph nodes because the body has an immune response at the site of the lymph nodes once tumor reaches this area, causing swelling and a noticeable neck mass, Dr. Prendes says. So, these working are, diagnosed in advanced stages.

    It can take up to 30 years for HPV-related throat cancer to appear, making It most common in adults between the ages of 40 and 60. The Oral cancer Foundation reports It's growing fastest among men, ages 25 to 55.

    Dr. Prendes says researchers have developed a clinical test that searches for the P16 molecular marker in biopsy samples, a marker that indicates HPV-related cancer. Successful treatment and cure rates are high if you know what to look for and know your risk, he says.

    Overall, HPV-related injuries are well to surgery and radiation. Between 90 and 95 percent of cases have five-year, disease-free survivorship rates, he says.

    Although researchers are still learning more about HPV-related throat cancer, the verdict about whether HPV is truly to blame is in, Dr. Prendes says.

    "I don't think anyone in our field or any epidemiologist would argue the link between HPV and throat cancer at this point," he says.

    2018年4月14日星期六

    Surpass yourself, believe in yourself, our family members.

    The management that promotes innovation must win in fierce competition, and only through innovation can the competitive advantage of the organization be formed. Innovation means that organizations make meaningful changes to products, services and processes, create new value for the organization's stakeholders, and take the organization's performance to a new level. Innovation should not be limited to product and technology innovation alone, but should be guided by the improvement of customer satisfaction, so that it can be integrated into the organization's various tasks, and innovations in concepts, institutions, mechanisms, processes, and markets can be managed. Fact-Based Management Fact-based management is a scientific attitude. It means that the management of an organization must be based on the measurement and analysis of its performance. Measurement of performance can include: customer satisfaction, product and service quality.
    Drug research.
    Quality management.
    Monoclonal antibody.

    2018年4月13日星期五

    Target antitumor drugs.

    Targeted anti-tumor drugs are mostly tyrosine kinase inhibitors, mainly by imatini, both inside and outside the body. At the cellular level, it is possible to optionally inhibit the positive cell line cells phmyocytic lymphoblastic and acute lymphoblastic leukemia patients. Proliferation and apoptosis of fresh cells. In addition, imatini can inhibit the cell behavior of the growth factor, receptor stem cell factor, tyrosine kinase, and thus the growth factor and stem cell behavior. However, in the course of imatini's treatment, some patients gradually discovered that resistance to imatini was developed, mainly because of the mutation of the gene that expresses the abodase in these patients. A change in the amino acid of the lkinase that results in a change in the structure of the interaction between imatini and the genes on one side.In response to such drug resistance, a second generation kinase inhibitor was developed, such as dastatini, for the treatment of non-small cell lung cancer, selective epidermal growth factor receptor and tyrosine kinase, Efficient oral communication, reasonable expression of growth factor receptor tyrosine kinase inhibitor, etrodandrotiini and use of treatment and for treatment, Multiple targets for metastasis of cancer cells or for mesomesenchymal tumors of the intestinal tract tolerant of imatini to a distance of three levels of uninhibitors.The multi-target therapy for advanced renal cell carcinoma is the Anshan kinase inhibitor, which is a new oral type of empty tumor drug that acts on many chickens and no eight percent. On the one hand, by a 2F segment kinase activity, the signal conduction path is blocked, and the tumor proliferation is directly induced and suppressed. On the other hand, vascular endothelial growth factor receptor has always needed to activate receptor tyrosine kinase, inhibit tumor angiogenesis, and firmly inhibit tumor growth.The right soil of the five high hb receptor has been used as a supplement to antitumor treatment. The structure of the dansk jopalolos joazazza Joaquin drugs is characterized by the structure of both the cecar money or its electrons in an equal row leading to the group ester. Most of the paper miscellaneous links are more complex, usually connected to the desquamate, similar Handan and Korean double rings.
    Active small molecular compounds.
    Monoclonal antibody, polyclonal antibody, recombinant protein, active protein, natural protein.

    Prediction of drug interactions.

    The combination drug is the conventional method of clinical drug treatment,The purpose is to improve the efficacy, reduce the toxicity, but the combination of drugs without purpose can not improve the efficacy, but increase the incidence of adverse drug reactions.Moreover, the incidence of adverse drug reactions may increase and increase with the types of drugs used.In conjunction with drugs, efforts should be made to avoid adverse drug interactions that reduce efficacy or increase toxicity.In order to effectively predict adverse drug interactions, drug researchers are required to carry out screening and early detection during the development of new drugs and the possible drug interactions.Reduce the risk of clinical drugs.On the one hand, clinical medical workers should have a full grasp of the nature of drugs, according to the situation of the disease to carry out a reasonable treatment program.Effective methods of avoiding adverse drug interactions and predicting drug interactions include in vitro camellia, which predicts individual predictions based on in vitro metabolic data.
    First, in vitro camellia.
    It has become an effective way to determine the future of drug development.Prior to the clinical study, mammal tests were used to screen for drug interactions, but because animals and people do not express or regulate their drug metabolism, There are differences in such areas as results and clinical practice and sometimes there is a big gap.In vitro, the most mature tools for the study of drug metabolism are related to cytochrome P450, a superior family of meta-cap.These enzymes are responsible for the metabolism of most drugs in the body, so the liver tissue slides of liver cells of liver cells of liver cells of liver cells are recombinant and CYP has been used to assess whether candidate drugs can affect the metabolism of another drug.

    The second, based on in vitro metabolic data.
    It is one of the effective methods for quantitatively predicting drug interactions in the body by using in vitro metabolic data to construct mathematical models.
    The method is mainly used for conservative predictions of severe drug interactions, which can eliminate false negative results and maximize drug interactions during drug development.
    The third, according to the patient's individual drug interaction prediction.
    Be familiar with the basic characteristics of drugs, including drugs, pharmacokinetics and pharmacodynamics, which are very important to predict the clinical drug interactions, and the most obvious types of clinical drug interactions. It's almost a drug called Wu Xiaoqiang, whose medicinal effects are shaking.
    For example, the cytotoxic drugs digoxin, warfarin blood sugar.
    The safe range of these drugs, the effect of the interaction of small drugs, the concentration of blood drugs outside the treatment window during a period of time, leading to a decline in efficacy or toxicity, Clinical use of drugs should be familiar with the main types of drugs that affect CPR, including the main gifts, inhibitors, luring agents, drug interactions that can occur in a short period of time. Others require treatment for several days or weeks to several weeks.For example, chloramphenicol has a long half-life and it takes several weeks for the effect,If the main management of C9 rabbit C9 metabolism drug treatment may still have no inhibition, resulting in poor clinical results.
    A combination of small molecular compounds used in drug research.
    Monoclonal antibody, polyclonal antibody, recombinant protein.
    Enzyme-linked immune kit

    2018年4月1日星期日

    Einstein's three big mistakes.

    Einstein was also a great man, and of course he would make mistakes, even if he had made mistakes in physics, and Einstein admitted that he would make mistakes. He thought the biggest mistake he had made was to put forward universe constant.General relativity predicts that the universe is either expanding or contracting, when Einstein's theory of relativity, physicists think that the universe is static, in order to solve this contradiction. There is also a cosmic constant in the formula of general relativity.Let the universe become static, and after Hubble discovered that the universe was expanding, regretted it, so he counted the universe as the biggest mistake he had made.
    But in recent years, the discovery of Montenegro on this issue may not be so big, after the initial big bang, the universe has been expanding, but the gravity of the matter that is distributed in the universe. It will also try to pull the universe back, by the influence of gravity, in theory, that the expansion of the universe should be slower and slower, and astronomers predict the supernova.How much of the expansion of the universe has slowed down in the past billions of years? The result is unexpected, the expansion of the universe not only has not been reduced, but is accelerating, which means that there is some unknown mysterious energy in the universe, called dark energy to counteract the role of gravity.
    This will allow the universe to expand faster and faster, and some physicists think that the universe should always be counted at home, and let him express dark energy, if that is the case.  Einstein is right in a way.
    Einstein thought he was wrong, and he did not think he was right about his criticism of quantum mechanics, though he believed he was right, but now it seems likely to be wrong. Because of the study of the photoelectric effect, Einstein was regarded as one of the fathers of quantum.But he thinks that quantum mechanics is correct, but not complete, there must be unknown factors that can explain the observable quantum phenomenon, in order to find the loopholes of quantum mechanics. Einstein put forward some thought experiments, and most of them could not stand the sale, but one of the most famous thought experiments was impeccable. This thought experiment 33 boduoersiji Rosen published a paper in '1935, physics is real, and quantum mechanics describes being completely blown up.This important paper was later written under the initials of the three masterpieces.
    Natural high purity compounds.
    Monoclonal antibodies.